Some diseases and cancers everyone has heard of. Others are relatively unknown by the general public until someone famous comes down with the disease. Suddenly you hear about this condition on the news every night and there are news shows featuring everything you ever wanted to know about this disease
Non-Hodgkin lymphoma is one such disease. There have been several very famous victims of non-Hodgkin lymphoma, including Jacqueline Kennedy Onassis, Mickey Mantle and King Hussein of Jordan.
Non-Hodgkin lymphoma is a form of cancer that affects the white blood cells. It is more than one type of cancer. Among the white blood cells are lymphocytes. There are B cell and T cell lymphocytes. Both can be involved in non-Hodgkin lymphoma but usually, it is either one or the other. Doctors are able to determine whether a cancer is Hodgkin or non-Hodgkin lymphoma by the presence or absence of the Reed Sternberg cell. If it is not present then it is non-Hodgkin lymphoma.
There are no definitive causes of this form of cancer. It is not inherited - it has been studied and there are no indications that the mutations in DNA that can be evident in people who have non-Hodgkin lymphoma were there when they were born. It is thought that they occurred at some point during their life. They can be caused by exposure to radiation or chemicals, and there are some indications that infections can also result in the mutant DNA.
It is known that there are some risk factors for lymphoma in general. Though many people who have the risk factors don’t get lymphoma and many people who don’t have the risk factors do.
Lymphocytes are the cells from which the B cells and the T cells are made. They are part of the immune system. The fact that a person’s immune system has been compromised by things such as HIV, organ transplant or an inherited condition is a definite risk factor. Another risk factor is the presence of an autoimmune disease such as rheumatoid arthritis or lupus.
Chronic infections also increase the risk of developing lymphoma, and infections such as Epstein Barr and H. pylori. Exposure to certain chemicals especially pesticide and herbicides are felt to be a causal factor in the developing lymphoma. The older you get, the more your risk increases as far as developing this cancer, and if you are a man your risk is greater.
Non-Hodgkin lymphoma can be very serious and it can cause death. It starts in the lymph nodes and can travel through the lymph system. In some case,s it is very slow acting and the doctor may take a watch and see attitude. If it is aggressive then the treatment will also have to be aggressive and can involve radiation and/or chemotherapy.
The diagnosis of non-Hodgkin lymphoma is not necessarily a death sentence but you need to know what cells are involved and what stage your disease is in. With the correct treatment, your prognosis should be good.
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